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Fig. 4 | Journal of Ovarian Research

Fig. 4

From: Integration of single-cell RNA-seq and bulk RNA-seq data to construct and validate a cancer-associated fibroblast-related prognostic signature for patients with ovarian cancer

Fig. 4

Identification of the hub predictive genes to construct a risk signature. (A) Volcano plot of differentially expressed genes of cancer and normal tissues in TCGA cohort; (B) Volcano plot of prognosis-related genes identified from univariate Cox regression analysis; (C) The trajectory of each independent variable with lambda; (D) Plots of the produced coefficient distributions for the logarithmic (lambda) series for parameter selection (lambda); (E) The multivariate Cox coefficients for each gene in the risk signature. (F) and (G) ROC curves of risk model constructed by 6 genes in TCGA cohort and GEO cohort; (H) and (I) K-M curves of risk model constructed by 6 genes in TCGA cohort and GEO cohort

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Journal of Ovarian Research

ISSN: 1757-2215

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